CASE REPORT
Anaplastic Large Cell Lymphoma ALK-Negative: About a Rare Pediatric Case Report
Louachama Ouidad1, *, Elbaz Meriem2, El Houdzi Jamila1
1 Department of Pediatric Hematology and oncology, University Hospital Mohammed VI, Marrakesh
separate by comma, Morocco
2 Department of Pediatric Hematology and oncology, Faculty of Medicine, University Cadi Ayad, Marrakesh, Morocco
Article Information
Identifiers and Pagination:
Year: 2020Volume: 10
First Page: 3
Last Page: 5
Publisher Id: TOPEDJ-10-3
DOI: 10.2174/1874309902010010003
Article History:
Received Date: 07/01/2020Revision Received Date: 03/04/2020
Acceptance Date: 02/05/2020
Electronic publication date: 16/06/2020
Collection year: 2020
© 2020 Ouidad et al.
open-access license: This is an open access article distributed under the terms of the Creative Commons Attribution 4.0 International Public License (CC-BY 4.0), a copy of which is available at: (https://creativecommons.org/licenses/by/4.0/legalcode). This license permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
open-access license: This is an open access article distributed under the terms of the Creative Commons Attribution 4.0 International Public License (CC-BY 4.0), a copy of which is available at: (https://creativecommons.org/licenses/by/4.0/legalcode). This license permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
Abstract
Introduction:
Anaplastic Large Cell Lymphomas (ALCL) are rare in childhood but clinically aggressive. The contemporary World Health Organization (WHO) classification of hematologic malignancies recognizes two distinct subtypes of systemic ALCL: Anaplastic Lymphoma Kinase (ALK)-negative, and ALK-positive.
Case report:
We report a rare pediatric observation of cutaneous nodule revealing an Anaplastic Large Cell Lymphoma (ALCL) ALK - cutaneous, muscular and ganglionic. It was classified according to who classification, treated by polychemotherapy with good outcome.
Conclusion:
ALCL encompasses several distinct clinicopathologic entities with unique genomic under printing. This rare pediatric observation of ALCL presents a new discussion on a pathology still incompletely known.
Keywords: Anaplastic large cell lymphoma, Negative ALK, Child, Polychemotherapy, Ultrasound, Hematologic malignancies.
