Anaplastic Large Cell Lymphoma ALK-Negative: About a Rare Pediatric Case Report
Louachama Ouidad1, *, Elbaz Meriem2, El Houdzi Jamila1
Identifiers and Pagination:Year: 2020
First Page: 3
Last Page: 5
Publisher Id: TOPEDJ-10-3
Article History:Received Date: 07/01/2020
Revision Received Date: 03/04/2020
Acceptance Date: 02/05/2020
Electronic publication date: 16/06/2020
Collection year: 2020
open-access license: This is an open access article distributed under the terms of the Creative Commons Attribution 4.0 International Public License (CC-BY 4.0), a copy of which is available at: (https://creativecommons.org/licenses/by/4.0/legalcode). This license permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
Anaplastic Large Cell Lymphomas (ALCL) are rare in childhood but clinically aggressive. The contemporary World Health Organization (WHO) classification of hematologic malignancies recognizes two distinct subtypes of systemic ALCL: Anaplastic Lymphoma Kinase (ALK)-negative, and ALK-positive.
We report a rare pediatric observation of cutaneous nodule revealing an Anaplastic Large Cell Lymphoma (ALCL) ALK - cutaneous, muscular and ganglionic. It was classified according to who classification, treated by polychemotherapy with good outcome.
ALCL encompasses several distinct clinicopathologic entities with unique genomic under printing. This rare pediatric observation of ALCL presents a new discussion on a pathology still incompletely known.